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SPNS Initiative: Prevention with HIV-Infected Persons Seen in Primary Care Settings, 2003-2007


The Special Projects of National Significance (SPNS) Prevention with Positives Initiative was designed to address the need for prevention interventions targeting people living with HIV receiving treatment in clinical care. The initiative sought to prevent transmission to uninfected persons and to prevent re-infection among people already living with HIV. The University of California, San Francisco Center for AIDS Prevention Studies served as the Evaluation and Support Center for the initiative, conducting a multi-site evaluation of the interventions to assess their effectiveness, feasibility, and costs.

Fifteen clinical demonstration sites were funded to implement and evaluate innovative prevention interventions for people living with HIV seen in primary care settings. These demonstration project grant recipients included: DeKalb County Board of Health (Decatur, GA); Drexel University School of Public Health (Philadelphia, PA); El Rio Santa Cruz Neighborhood Health Center (Tucson, AZ); Fenway Community Health Center (Boston, MA); Johns Hopkins University (Baltimore, MD); Los Angeles County Department of Health Services (CA); Mount Sinai Hospital (Chicago, IL); St. Luke's Roosevelt Hospital Center (New York, NY); University of Alabama at Birmingham; University of California, Davis (Sacramento, CA); University of California, San Diego; University of Miami School of Medicine (FL); University of North Carolina, Chapel Hill; University of Washington (Seattle, WA); and Whitman-Walker Clinic (Washington, DC).

Journal Articles

Marseille E, Shade SB, Myers J, & Morin S. The cost-effectiveness of HIV prevention interventions for HIV-infected patients seen in clinical settings. Journal of Acquired Immune Deficiency Syndromes, March 2011; 56 (3): e87-e94. PubMed Abstract

Myers JJ, Shade SB, Rose CD, Koester K, Maiorana A, Malitz FE, Bie J, Kang-Dufour MS, & Morin SF.  Interventions Delivered in Clinical Settings are Effective in Reducing Risk of HIV Transmission Among People Living with HIV: Results from the Health Resources and Services Administration (HRSA)'s Special Projects of National Significance Initiative. AIDS and Behavior, June 2010; 14 (3): 483-492. PubMed Abstract

Estes LJ, Lloyd LE, Teti M, Raja S, Bowleg L, Allgood KL, & Glick N. Perceptions of Audio Computer-Assisted Self-Interviewing (ACASI) among Women in an HIV Positive Prevention Program. PLoS ONE, 5 (2): e-published February 10, 2010. Full Text

Iverson EF, Balasuriya D, Garc?a GP, Sheng M, Richardson JL, Stoyanoff S, & King JB.  The Challenges of Assessing Fidelity to Physician-Driven HIV Prevention Interventions: Lessons Learned Implementing Partnership for Health in a Los Angeles HIV Clinic.  AIDS and Behavior, November 2008; 12 (6): 978-988. PubMed Abstract

Grodensky CA, Golin CE, Boland MS, Patel SN, Quinlivan EB, & Price M.  Translating concern into action: HIV care providers' views on counseling patients about HIV prevention in the clinical setting.  AIDS and Behavior, May 2008; 12 (3): 404-411. PubMed Abstract

Malitz FE and Eldred L. Evolution of the special projects of national significance prevention with HIV-infected persons seen in primary care settings initiative.  AIDS and Behavior, September 2007; 11 (5 Supplement):  S1-S5.  No abstract available.

Morin SF, Myers JJ, Shade SB, Koester K, Maiorana A, & Rose CD.  Predicting HIV transmission risk among HIV-infected patients seen in clinical settings.  AIDS and Behavior, September 2007; 11 (5 Supplement): S6-S16. PubMed Abstract

Koester KA, Maiorana A, Vernon K, Myers J, Rose CD, & Morin S.  Implementation of HIV prevention interventions with people living with HIV/AIDS in clinical settings: challenges and lessons learned.  AIDS and Behavior, September 2007; 11 (5 Supplement): S17-S29. PubMed Abstract

Myers JJ, Rose CD, Shade SB, Koester KA, Maiorana A, Malitz F, Steward WT, & Morin SF. Sex, risk and responsibility: provider attitudes and beliefs predict HIV transmission risk prevention counseling in clinical care settings. AIDS and Behavior, September 2007; 11 (5 Supplement): S30-S38. PubMed Abstract

Grimley DM, Bachmann LH, Jenckes MW, & Erbelding EJ. Provider-delivered, theory-based, individualized prevention interventions for HIV positive adults receiving HIV comprehensive care.  AIDS and Behavior, September 2007; 11 (5 Supplement): S39-S47.  PubMed Abstract

Callahan EJ, Flynn NM, Kuenneth CA, & Enders SR. Strategies to reduce HIV risk behavior in HIV primary care clinics: brief provider messages and specialist intervention.  AIDS and Behavior, September 2007; 11 (5 Supplement): S48-S57.  PubMed Abstract

Zuniga ML, Baldwin H, Uhler D, Brennan J, Olshefsky AM, Oliver E, & Mathews WC. Supporting Positive Living and Sexual Health (SPLASH): a clinician and behavioral counselor risk-reduction intervention in a university-based HIV clinic.  AIDS and Behavior, September 2007; 11 (5 Supplement): S58-S71.  PubMed Abstract

Golin CE, Patel S, Tiller K, Quinlivan EB, Grodensky CA, & Boland M. Start Talking About Risks: development of a Motivational Interviewing-based safer sex program for people living with HIV. AIDS and Behavior, September 2007; 11 (5 Supplement): S72-S83. PubMed Abstract

Nollen C, Drainoni ML & Sharp V. Designing and delivering a prevention project within an HIV treatment setting: lessons learned from a specialist model. AIDS and Behavior, September 2007; 11 (5 Supplement): S72-S83. PubMed Abstract

Estrada BD, Trujillo S, & Estrada AL. Supporting Healthy Alternatives through Patient  Education: a theoretically driven HIV prevention intervention for persons living with HIV/AIDS. AIDS and Behavior, September 2007; 11 (5 Supplement): S95-S105.  PubMed Abstract

Teti M, Rubinstein S, Lloyd L, Aaron E, Merron-Brainerd J, Spencer S, Ricksecker A, & Gold M.  The Protect and Respect program: a sexual risk reduction intervention for women living with HIV/AIDS. AIDS and Behavior, September 2007; 11 (5 Supplement): S106-S116.  PubMed Abstract

Knauz RO, Safren SA, O'Cleirigh C, Capistrant BD, Driskell JR, Aguilar D, Salomon L, Hobson J, & Mayer KH.  Developing an HIV-Prevention Intervention for HIV-Infected Men Who Have Sex with Men in HIV Care: Project Enhance.  AIDS and Behavior, September 2007; 11 (5 Supplement): S117-S126.  PubMed Abstract

Raja S, McKirnan D, & Glick N. The Treatment Advocacy Program--Sinai: a peer-based HIV prevention intervention for working with African American HIV-infected persons.  AIDS and Behavior, September 2007; 11 (5 Supplement): S127-S137.  PubMed Abstract

Steward WT, Koester KA, Myers JJ, & Morin SF.  Provider fatalism reduces the likelihood of HIV-prevention counseling in primary care settings.  AIDS and Behavior, January 2006; 10 (1): 3-12.  PubMed Abstract

Myers JJ, Steward WT, Charlebois E, Koester KA, Maiorana A, & Morin SF. Written clinic procedures enhance delivery of HIV "prevention with positives" counseling in primary health care settings.  Journal of Acquired Immune Deficiency Syndromes, 37 (Supplement 2): S95-S100. PubMed Abstract

Morin SF, Koester KA, Steward WT, Maiorana A, McLaughlin M, Myers JJ, Vernon K, & Chesney MA. Missed opportunities: prevention with HIV-infected patients in clinical care settings.  Journal of Acquired Immune Deficiency Syndromes, 36 (4): 960-966.  PubMed Abstract

Part F - SPNS Resources

Part F - SPNS Products and Publications

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SPNS Staff

Adan Cajina
Branch Chief

Pamela Belton
Public Health Analyst

Renetta Boyd
Public Health Analyst

Johanna Goderre
Health Scientist

John Hannay
Public Health Analyst

Chau Nguyen
Public Health Analyst

Natalie Solomon
Public Health Analyst

Melinda Tinsley
Public Health Analyst

Jessica Xavier
Health Scientist